TOKAI HIT
Stress-free Microscale Perfusion with “Plug and Play
Construction of Microphysiological system is a Tokai hit
Micro ×Vivo Solutions
In recent years, microscale research has been conducted in a wide range of fields such as medicine, biotechnology, and chemistry,
Various operations and analyses that were difficult to perform with conventional technologies are now being conducted.
One of the most advanced technologies attracting attention is "Microphysiological systems".
Microphysiological systems simulate the functions of living tissues and organs.
By reproducing an environment that is micro and close to that of a living body, it is expected to evaluate the effects and toxicity of drugs and to elucidate the mechanisms of diseases.
The “Mi” also stands for “My,” and we hope to propose tailor-made solutions for researchers' original experiments.
We hope to propose tailor-made solutions for researchers' original experiments.
Features
"Plug and Play” for any microfluidic chip
Support for everything from incubator culture to live cell imaging
Flexible customization of containers and pumps
It supports a wide range of applications such as perfusion culture in incubators and time-lapse imaging.
Compatible with any microfluidic chip, including home-made chips.
Simply connect your chip to realize micro perfusion.
As well as 35 mm dishes and microfluidic chips,
A variety of commercially available vessels such as cell culture inserts and cell desks can also be used.
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Microfluidic Chip + Constant Pressure/Constant Flow Perfusion
The BPU constant-pressure pumping unit enables perfusion with a variety of microfluidic tips, including those of your own making. Simply by connecting the chip, perfusion that mimics pulsatile motion or perfusion with controlled flow and pressure can be realized. Two pumps are provided as standard equipment, allowing experiments under different pressure and flow conditions.
This product is especially suitable for experiments on vascular and circulatory systems.
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Perfusion with Culture Insert
Tokai Hit has also developed a pump system that enables perfusion culture by utilizing commercially available cell culture inserts as they are. Since a commercially available 35 mm dish is used as the base of the culture surface, microscopic observation is also possible. In addition, the system has two culture vessels, each of which can be used to freely change organ sets, making it useful for analysis of inter-organ crosstalk mechanisms.
This product is particularly suitable for studies requiring mechanical flow, such as cilia in the lungs and intestines, and for pharmacokinetic and toxicological evaluation studies.
This culture system enables perfusion culture with “Cell Desk LF” manufactured by Sumitomo Bakelite. By using “Cell Desk LF” with a plastic coverslip, cells can be easily collected and transferred, and can be removed for fluorescent observation.
We recommend this system for easy perfusion culture using a coverslip.
Perfusion Startup Kit
Perfusion and medium exchange can be performed using commercially available 35 mm dishes.
Perfusion can be performed with the lid on, preventing the risk of contamination.
Recommended for those who perform perfusion culture for the first time or for those who prefer simple medium exchange.